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By Laura Fisher 27 May 2017

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Microfluidic device shows that antiperspirants control sweating by forming pore-pluggingaggregateswith perspiration proteins

Schematic drawing of a sweat gland cross section next to a photo of the microfluidic ‘sweat-pore-on-a-chip’ device (ACH = aluminium chlorohydrate, one of the main components in antiperspirants)

Researchers in France have made a microfluidic device that mimics sweat pores, showing that perspiration proteins are essential to the way deodorants work.

Antiperspirants control sweating through the interaction of aluminium salts with sweat. A number of theories have been put forward for how these products work; the most widely accepted one being that the salts diffuse into the sweat duct and hydrolyse in contact with sweat, forming an aluminium hydroxide plug that blocks sweat flow.

The truth maybe a little more complicated, however, as Bernard Cabane from L’Oreal, Jean-Baptiste Galey from ESPCI ParisTech and colleagues have discovered. They have built a microfluidic T-junction that mimics sweat ducts, and allows them to study the interactions between sweat and aluminium chlorohydrate (ACH) in real time. The device consists of a surface channel filled with ACH, and an orthogonal channel into which they pump sweat. Using time and spatially resolved small-angle x-ray scattering, they studied the structure and composition of the plugs formed, and how they block the sweat duct.

The results show that ACH aggregates with proteins in the sweat, forming a membrane that extends across the duct. It then collects further proteins and grows to form a plug that blocks the duct entirely. ‘Contrary to previously published works, we demonstrate that sweat proteins are necessary for pore plugging, in spite of their very low concentration, because they are constantly brought by the flow,’ says Cabane.

‘This team has developed an elegant microfluidics device to mimic the sweat gland,’ comments Robert Prud’homme , an expert in molecular level interactions at Princeton University in the US. ‘They might have stopped with just the visual observations of the formation of plugs, but they have upped the ante and conducted beautiful small angle scattering experiments to enable quantitative statements about the protein aggregation driven by aluminium ion binding.’

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Stop trying to “manage” your feelings, and do this instead.

[Photo: Michael Rougier/The LIFE Picture Collection/Getty Images]
5 minute Read

Listening is a skill–but you already know that. There’s plenty of advice on how to become a better listener and why it’s so important . But while you can pick up a few tactics to improve the way you listen, another route is simply to tap into that other skill set you can’t stop hearing about : emotional intelligence. Here are a few straightforward ways to use your feelings to listen better.


The starting point for emotional listening is reinforcement–nodding your head, or saying “yes” and “I understand”–but it doesn’t stop there. Show that you empathize by using phrases like, “I can see why you feel that way” or, “That must have been a difficult decision for you.” This encourages others to open up and share their feelings, not just their thoughts and ideas.

Related: Emotional Intelligence Is The Real Secret To Getting Promoted Faster


You’re in a meeting with your boss when he takes a quick call from another executive. And then you notice his tone sharpen. He sounds slightly defensive, and after hanging up seems a little restless and distracted. You might feel like it’s more polite to overlook those cues, but you shouldn’t. Ask, “Should we adjourn and meet another time?” Even if he says, “No, let’s continue,” you’ve shown that you’ve listened emotionally. Your boss might even share something of the conversation with you.

Emotional listening requires studying someone’s expressions, tone of voice, and body language to draw conclusions about how they’re feeling. We all do that involuntarily already, but the key is to use that nonverbal data consciously and know how to respond to it.

inRead invented by Teads

I remember a meeting at my company where we seemed to have reached a conclusion on a contentious issue, but one participant had his arms crossed and his chin tilted downward. Another team member took note and spoke up: “I don’t think you’re comfortable with this decision. We need to know that you are comfortable.” That acknowledgment was all it took to reopen the conversation, and it ultimately led to a better resolution that everyone felt good about.

Some people may not want to stall decisions, but even when they don’t raise objections their nonverbal signals give away their feelings. Emotionally intelligent listeners “hear” those unspoken signs loud and clear.

  • About

    The primary objective of the FELIX project (FEderated Test-beds for Large-scale Infrastructure eXperiments) is to create a common framework in which users can request, monitor and manage a slice provisioned over distributed and distant Future Internet experimental facilities in Europe and Japan.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. 608638 and National Institute of Information and Communications Technology, Japan The scientific/academic work is financed from financial resources for science in the years 2013 - 2016 granted for the realization of the international project co-financed by Polish Ministry of Science and Higher Education Copyright FELIX EU-JP © 2013-2016.